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The Ebola Virus
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The Ebola virus is a type of ribonucleic acid (RNA) virus that causes the disease known as Ebola hemorrhagic fever (also called Ebola).
The Ebola virus was first recognized in the Democratic Republic of the Congo (formerly Zaire), in Africa, and got its name from a river there.
There are two members of a family of RNA viruses called Filoviridae, and the Ebola virus is one of them. There are four identified subtypes of the virus. Three of the four have caused disease in humans:
The fourth Ebola virus subtype, Ebola-Reston, has caused disease in nonhuman primates, but not in humans.
On the basis of available evidence and the nature of similar viruses, researchers believe that the virus is zoonotic (animal-borne) and is normally maintained in an animal host that is native to the African continent. However, the exact locations, origin, and natural habitat (known as the natural reservoir) of the Ebola virus remain unknown. Research scientists continue to search for the exact animal host.
Ebola-Reston was isolated from infected cynomolgus monkeys that were imported from the Philippines to the United States and Italy, and is probably associated with a similar host. The virus is not known to be native to other continents, such as North America.
Ebola outbreaks typically appear sporadically. Confirmed cases of infections have been reported in:
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